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[翰佳老師影音課程] 14-3 三種酵素催化的實例探討
  • 生物化學 (二)
  • [在課程開始之前]
  • 林翰佳老師評分標準
  • 如何作筆記?心智圖 (mind map) 示範
  • 網路流傳的十大筆記方法,總應該有適合你的方法吧!
  • 商業周刊 - 從大賣場看瑞士和台灣學生哪裡不一樣!開學了,瑞士學生不買「書套」而買「卷宗夾」,因為...
  • [Topic 1] Chapter 13 酵素動力學 Enzyme kinetics
  • [上課講義] Chap 13 酵素與酵素動力學
  • [簡介] 可汗學院的短片,介紹「酵素」的基本知識
  • [翰佳老師影音課程] 13-1 有關酵素,你該知道的一些事
  • [翰佳老師影音課程] 13-2 酵素動力學,微積分被當的不要怕!
  • [翰佳老師影音課程] 13-3 酵素抑制劑
  • [課程補充資料]
  • [大突破] DeepMind 人工智慧推測蛋白質立體構造準確度大增
  • [Topic 2] Chapter 14 酵素催化原理與作用機轉
  • [上課講義] Chap 14 酵素催化原理
  • [翰佳老師影音課程] 14-1 更深入一點看酵素的催化原理
  • [翰佳老師影音課程] 14-2 各種催化的機制
  • [翰佳老師影音課程] 14-3 三種酵素催化的實例探討
  • 課程補充資料
  • [Topic 3] Chapter 15 酵素活性調節
  • [上課講義] Chap 15 酵素活性調節
  • [翰佳老師影音課程] 15-1 影響酵素活性的因素有那些
  • [翰佳老師影音課程] 15-2 Allosteric regulation 異位調控現象與理論
  • [翰佳老師影音課程] 15-3 以血紅素攜帶氧氣的能力為例,看蛋白質的調控
  • [Topic 4] Chapter 17 代謝的概念 (請自行閱讀,老師不考)
  • B_BC_chap17
  • Chapter 17 影音
  • [Topic 5] Chapter 18 醣解作用
  • B_BC_chap18
  • [翰佳老師影音課程] 18-1 醣解作用第一階段前五個反應
  • [翰佳老師影音課程] 18-2 醣解作用第二階段後五個反應
  • [翰佳老師影音課程] 18-3 其他醣類進入醣解作用,醣解作用與癌症
  • [Topic 6] Chapter 19 檸檬酸循環
  • B_BC_chap19
  • [翰佳老師影音課程] 19-1 檸檬酸循環作用第一階段前五個反應
  • [翰佳老師影音課程] 19-2 檸檬酸循環作用第二階段後四個反應
  • [翰佳老師影音課程] 19-3 檸檬酸循環補充反應與相關反應
  • [Topic 8] Chapter 20 電子傳遞鏈
  • B_BC_chap20
  • 20 章投影片
  • [翰佳老師影音課程] 20-1 還原電位與電子傳遞
  • [翰佳老師影音課程] 20-2 四大複合體與質子梯度
  • [翰佳老師影音課程] 20-3 粒線體 ATP 合成酶、氧化磷酸化效率以及細胞凋亡
  • [外部影片] 電子傳遞鏈、細胞呼吸的動畫
  • [外部影片] 看看 ATP Synthase 的作用機制
  • [外部影片] ATP synthase 作用機制 (這部影片更擬真)
  • [Topic 9] Chapter 21 光合作用
  • B_BC_chap21
  • [翰佳老師影音課程] 21-1 光合作用
  • [翰佳老師影音課程] 21-2 光反應系統
  • [翰佳老師影音課程] 21-3 暗反應、光呼吸以及 C4 植物
  • [外部影片] Photosynthesis (看看外國老師怎麼教?)
  • [外部影片] Photosynthesis 動畫
  • 最新版 Chap 21 光合作用投影片
  • [Topic 7] Chapter 22 醣質新生
  • B_BC_chap22
  • [翰佳老師影音課程] 22-1 醣質新生
  • [翰佳老師影音課程] 22-2 肝醣代謝與五碳醣磷酸途徑
  • 葡萄糖-6-磷酸脫氫酶缺乏症 (蠶豆症是怎麼一回事?)
  • ch23
  • 2016 Ch23 Fatty Acid Catabolism
  • CH 23
  • ch24
  • 2016 CH24 Lipid biosynthesis
  • CH 24
  • ch25
  • 2016CH25Nitrogen Acquisition and Amino Acid Metabolism
  • 2016CH25Nitrogen Acquisition and Amino Acid Metabolism.fsp
  • ch26
  • 2016CH26Synthesis and Degradation of Nucleotides
  • 2016CH26Synthesis and Degradation of Nucleotides
  • P.902-P.911 & Chapter23
  • P.902-P.911 & Chapter23
  • 索引
  • 重點
  • 討論
  • 筆記
長度: 42:52, 發表時間 : 2016-03-10 09:54
觀看次數 : 2,947
  • 00:06
    1. Slide 1
  • 00:50
    2. 14.5 What Can Be Learned From Typical Enzyme Mechanisms?
  • 02:01
    3. Example 1: The Serine Proteases Family
  • 02:34
    4. zymogen
  • 01:36
    5. Catalytic Triad
  • 01:57
    6. Similarity of 3 Serine Proteases
  • 01:00
    7. The Catalytic Triad of the Serine Proteases
  • 02:35
    8. The substrate-binding pockets determine the substrate selectivity
  • 00:26
    9. Serine Protease Binding Pockets are Adapted to Particular Substrates
  • 01:32
    10. How to assay the activity of protease?
  • 00:08
    11. Serine Protease Binding Pockets are Adapted to Particular Substrates
  • 00:12
    12. How to assay the activity of protease?
  • 00:12
    13. Burst kinetics tell the mechanism of serine protease
  • 00:11
    14. How to assay the activity of protease?
  • 01:18
    15. Burst kinetics tell the mechanism of serine protease
  • 00:41
    16. Serine Protease Mechanism
  • 01:50
    17. The Serine Protease Mechanism in Detail 1/5
  • 02:10
    18. The Serine Protease Mechanism in Detail 2/5
  • 00:37
    19. The Serine Protease Mechanism in Detail 3/5
  • 00:31
    20. The Serine Protease Mechanism in Detail 4/5
  • 00:27
    21. The Serine Protease Mechanism in Detail 5/5
  • 00:42
    22. Transition-State Stabilization in the Serine Proteases
  • 00:01
    23. The Serine Protease Mechanism in Detail 5/5
  • 00:09
    24. The Serine Protease Mechanism in Detail 4/5
  • 00:01
    25. The Serine Protease Mechanism in Detail 3/5
  • 00:01
    26. The Serine Protease Mechanism in Detail 2/5
  • 00:13
    27. The Serine Protease Mechanism in Detail 4/5
  • 00:12
    28. Transition-State Stabilization in the Serine Proteases
  • 00:37
    29. The “oxyanion hole”
  • 00:27
    30. Example 2: The Aspartic Proteases
  • 00:18
    31. Aspartic proteases play many roles in humans
  • 01:04
    32. The Aspartic Proteases
  • 00:33
    33. Aspartic Protease Mechanism
  • 02:01
    34. A Mechanism for the Aspartic Proteases
  • 00:39
    35. HIV-1 Protease
  • 00:45
    36. Proteolytic cleavage pattern for the HIV genome
  • 00:08
    37. Protease Inhibitors Block the Active Site of HIV-1 Protease
  • 00:03
    38. Proteolytic cleavage pattern for the HIV genome
  • 00:31
    39. Protease Inhibitors Block the Active Site of HIV-1 Protease
  • 00:30
    40. Protease Inhibitors Give Life to AIDS Patients
  • 00:14
    41. Protease Inhibitors Give Life to AIDS Patients
  • 00:34
    42. Example 3: Chorismate Mutase
  • 00:19
    43. Chorismate Mutase: A Model for Understanding Catalytic Power and Efficiency
  • 00:52
    44. Chorismate Mutase: A Model for Understanding Catalytic Power and Efficiency
  • 01:01
    45. Two possible mechanisms of chorismate rearrangement reaction
  • 00:32
    46. Use TSA to understand the chair mechanism of chorismate mutase
  • 00:53
    47. The structure of E. coli chorismate mutase
  • 00:43
    48. The Chorismate Mutase Active Site Favors a NAC
  • 00:31
    49. Slide 37
  • 01:04
    50. Formation of a NAC is facile in the chorismate mutase active site
  • 03:01
    51. To see is to believe!
  • 00:18
    52. End of Part 3
  • 00:33
    53. End of this class
附件
長度: 42:52, 發表時間 : 2016-03-10 09:54
觀看次數 : 2,947
附件
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