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2016CH25Nitrogen Acquisition and Amino Acid Metabolism.fsp
  • 生物化學 (二)
  • [在課程開始之前]
  • 林翰佳老師評分標準
  • 如何作筆記?心智圖 (mind map) 示範
  • 網路流傳的十大筆記方法,總應該有適合你的方法吧!
  • 商業周刊 - 從大賣場看瑞士和台灣學生哪裡不一樣!開學了,瑞士學生不買「書套」而買「卷宗夾」,因為...
  • [Topic 1] Chapter 13 酵素動力學 Enzyme kinetics
  • [上課講義] Chap 13 酵素與酵素動力學
  • [簡介] 可汗學院的短片,介紹「酵素」的基本知識
  • [翰佳老師影音課程] 13-1 有關酵素,你該知道的一些事
  • [翰佳老師影音課程] 13-2 酵素動力學,微積分被當的不要怕!
  • [翰佳老師影音課程] 13-3 酵素抑制劑
  • [課程補充資料]
  • [大突破] DeepMind 人工智慧推測蛋白質立體構造準確度大增
  • [Topic 2] Chapter 14 酵素催化原理與作用機轉
  • [上課講義] Chap 14 酵素催化原理
  • [翰佳老師影音課程] 14-1 更深入一點看酵素的催化原理
  • [翰佳老師影音課程] 14-2 各種催化的機制
  • [翰佳老師影音課程] 14-3 三種酵素催化的實例探討
  • 課程補充資料
  • [Topic 3] Chapter 15 酵素活性調節
  • [上課講義] Chap 15 酵素活性調節
  • [翰佳老師影音課程] 15-1 影響酵素活性的因素有那些
  • [翰佳老師影音課程] 15-2 Allosteric regulation 異位調控現象與理論
  • [翰佳老師影音課程] 15-3 以血紅素攜帶氧氣的能力為例,看蛋白質的調控
  • [Topic 4] Chapter 17 代謝的概念 (請自行閱讀,老師不考)
  • B_BC_chap17
  • Chapter 17 影音
  • [Topic 5] Chapter 18 醣解作用
  • B_BC_chap18
  • [翰佳老師影音課程] 18-1 醣解作用第一階段前五個反應
  • [翰佳老師影音課程] 18-2 醣解作用第二階段後五個反應
  • [翰佳老師影音課程] 18-3 其他醣類進入醣解作用,醣解作用與癌症
  • [Topic 6] Chapter 19 檸檬酸循環
  • B_BC_chap19
  • [翰佳老師影音課程] 19-1 檸檬酸循環作用第一階段前五個反應
  • [翰佳老師影音課程] 19-2 檸檬酸循環作用第二階段後四個反應
  • [翰佳老師影音課程] 19-3 檸檬酸循環補充反應與相關反應
  • [Topic 8] Chapter 20 電子傳遞鏈
  • B_BC_chap20
  • 20 章投影片
  • [翰佳老師影音課程] 20-1 還原電位與電子傳遞
  • [翰佳老師影音課程] 20-2 四大複合體與質子梯度
  • [翰佳老師影音課程] 20-3 粒線體 ATP 合成酶、氧化磷酸化效率以及細胞凋亡
  • [外部影片] 電子傳遞鏈、細胞呼吸的動畫
  • [外部影片] 看看 ATP Synthase 的作用機制
  • [外部影片] ATP synthase 作用機制 (這部影片更擬真)
  • [Topic 9] Chapter 21 光合作用
  • B_BC_chap21
  • [翰佳老師影音課程] 21-1 光合作用
  • [翰佳老師影音課程] 21-2 光反應系統
  • [翰佳老師影音課程] 21-3 暗反應、光呼吸以及 C4 植物
  • [外部影片] Photosynthesis (看看外國老師怎麼教?)
  • [外部影片] Photosynthesis 動畫
  • 最新版 Chap 21 光合作用投影片
  • [Topic 7] Chapter 22 醣質新生
  • B_BC_chap22
  • [翰佳老師影音課程] 22-1 醣質新生
  • [翰佳老師影音課程] 22-2 肝醣代謝與五碳醣磷酸途徑
  • 葡萄糖-6-磷酸脫氫酶缺乏症 (蠶豆症是怎麼一回事?)
  • ch23
  • 2016 Ch23 Fatty Acid Catabolism
  • CH 23
  • ch24
  • 2016 CH24 Lipid biosynthesis
  • CH 24
  • ch25
  • 2016CH25Nitrogen Acquisition and Amino Acid Metabolism
  • 2016CH25Nitrogen Acquisition and Amino Acid Metabolism.fsp
  • ch26
  • 2016CH26Synthesis and Degradation of Nucleotides
  • 2016CH26Synthesis and Degradation of Nucleotides
  • P.902-P.911 & Chapter23
  • P.902-P.911 & Chapter23
  • 索引
  • 重點
  • 討論
  • 筆記
長度: 3:24:48, 發表時間 : 2016-06-03 12:17
觀看次數 : 2,153
  • 00:25
    1. Slide 1
  • 03:43
    2. 1.The Nitrogen Cycle2.Amino Acid Biosynthesis3.Urea Cycle4.Amino Acid Catabolism5.Molecules Derived from Amino Acid(from Lehninger P902- 911)
  • 00:04
    3. Slide 3
  • 00:12
    4. The Nitrogen Cycle
  • 01:09
    5. How Do the Various Organic Forms of Nitrogen Arise?
  • 02:20
    6. The Nitrogen Cycle
  • 00:25
    7. How Do the Various Organic Forms of Nitrogen Arise?
  • 00:07
    8. The Nitrogen Cycle
  • 01:27
    9. How Do the Various Organic Forms of Nitrogen Arise?
  • 00:42
    10. Which Metabolic Pathways Allow Organisms to Live on Inorganic Forms of Nitrogen?
  • 01:08
    11. Nitrate Assimilation is the Principal Pathway for Ammonium Biosynthesis
  • 01:36
    12. Nitrogen Fixation Is by Nitrogenase Complex
  • 00:00
    13. Nitrate Assimilation is the Principal Pathway for Ammonium Biosynthesis
  • 00:00
    14. Which Metabolic Pathways Allow Organisms to Live on Inorganic Forms of Nitrogen?
  • 00:00
    15. How Do the Various Organic Forms of Nitrogen Arise?
  • 00:34
    16. The Nitrogen Cycle
  • 00:00
    17. How Do the Various Organic Forms of Nitrogen Arise?
  • 00:01
    18. Which Metabolic Pathways Allow Organisms to Live on Inorganic Forms of Nitrogen?
  • 00:01
    19. Nitrate Assimilation is the Principal Pathway for Ammonium Biosynthesis
  • 00:03
    20. Nitrogen Fixation Is by Nitrogenase Complex
  • 02:26
    21. The Fate of Ammonium
  • 03:23
    22. The Glutamate Dehydrogenase Reaction
  • 00:58
    23. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:00
    24. The Glutamate Dehydrogenase Reaction
  • 01:06
    25. The Fate of Ammonium
  • 00:01
    26. The Glutamate Dehydrogenase Reaction
  • 00:12
    27. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:13
    28. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:00
    29. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:00
    30. The Glutamate Dehydrogenase Reaction
  • 00:00
    31. The Fate of Ammonium
  • 00:00
    32. Nitrogen Fixation Is by Nitrogenase Complex
  • 00:16
    33. Nitrate Assimilation is the Principal Pathway for Ammonium Biosynthesis
  • 00:00
    34. Nitrogen Fixation Is by Nitrogenase Complex
  • 00:00
    35. The Fate of Ammonium
  • 00:00
    36. The Glutamate Dehydrogenase Reaction
  • 00:00
    37. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:29
    38. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:27
    39. The GDH/GS Pathway of Ammonium Assimilation
  • 00:00
    40. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:00
    41. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:08
    42. The Glutamate Dehydrogenase Reaction
  • 00:10
    43. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:05
    44. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:50
    45. The GDH/GS Pathway of Ammonium Assimilation
  • 00:00
    46. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 01:24
    47. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:26
    48. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:00
    49. The GDH/GS Pathway of Ammonium Assimilation
  • 01:23
    50. The GS/GOGAT Pathway of Ammonium Assimilation
  • 01:19
    51. The GDH/GS Pathway of Ammonium Assimilation
  • 00:46
    52. The GS/GOGAT Pathway of Ammonium Assimilation
  • 00:04
    53. The GDH/GS Pathway of Ammonium Assimilation
  • 01:13
    54. The GS/GOGAT Pathway of Ammonium Assimilation
  • 00:06
    55. The GDH/GS Pathway of Ammonium Assimilation
  • 00:00
    56. The GS/GOGAT Pathway of Ammonium Assimilation
  • 02:18
    57. The Subunit Organization of Bacterial Glutamine Synthetase
  • 10:02
    58. Page 850
  • 01:57
    59. Allosteric Regulation of Glutamine Synthetase by Feedback Inhibition
  • 00:57
    60. The Nitrogen Cycle
  • 00:02
    61. How Do the Various Organic Forms of Nitrogen Arise?
  • 00:01
    62. Which Metabolic Pathways Allow Organisms to Live on Inorganic Forms of Nitrogen?
  • 00:04
    63. Nitrate Assimilation is the Principal Pathway for Ammonium Biosynthesis
  • 00:03
    64. Nitrogen Fixation Is by Nitrogenase Complex
  • 00:26
    65. The Fate of Ammonium
  • 00:01
    66. The Glutamate Dehydrogenase Reaction
  • 00:00
    67. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:02
    68. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:44
    69. The GDH/GS Pathway of Ammonium Assimilation
  • 03:19
    70. The GS/GOGAT Pathway of Ammonium Assimilation
  • 00:16
    71. The Subunit Organization of Bacterial Glutamine Synthetase
  • 01:06
    72. Page 850
  • 00:43
    73. Allosteric Regulation of Glutamine Synthetase by Feedback Inhibition
  • 01:51
    74. Covalent Modification of GS: Adenylylation of Tyr397 in the Glutamine Synthetase
  • 00:01
    75. The cyclic cascade system regulating the covalent modification of GS
  • 00:04
    76. The cyclic cascade system regulating the covalent modification of GS
  • 00:23
    77. The cyclic cascade system regulating the covalent modification of GS
  • 00:07
    78. Covalent Modification of GS: Adenylylation of Tyr397 in the Glutamine Synthetase
  • 02:13
    79. The cyclic cascade system regulating the covalent modification of GS
  • 00:08
    80. Covalent Modification of GS: Adenylylation of Tyr397 in the Glutamine Synthetase
  • 01:53
    81. The cyclic cascade system regulating the covalent modification of GS
  • 00:10
    82. The cyclic cascade system regulating the covalent modification of GS
  • 00:00
    83. The cyclic cascade system regulating the covalent modification of GS
  • 00:34
    84. The cyclic cascade system regulating the covalent modification of GS
  • 00:00
    85. The cyclic cascade system regulating the covalent modification of GS
  • 00:00
    86. Covalent Modification of GS: Adenylylation of Tyr397 in the Glutamine Synthetase
  • 00:00
    87. Allosteric Regulation of Glutamine Synthetase by Feedback Inhibition
  • 00:00
    88. Page 850
  • 00:00
    89. The Subunit Organization of Bacterial Glutamine Synthetase
  • 00:03
    90. The GS/GOGAT Pathway of Ammonium Assimilation
  • 00:04
    91. The GDH/GS Pathway of Ammonium Assimilation
  • 00:00
    92. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:01
    93. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:13
    94. The Glutamate Dehydrogenase Reaction
  • 00:09
    95. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:00
    96. The Glutamate Dehydrogenase Reaction
  • 00:01
    97. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:00
    98. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:00
    99. The GDH/GS Pathway of Ammonium Assimilation
  • 00:00
    100. The GS/GOGAT Pathway of Ammonium Assimilation
  • 00:00
    101. The Subunit Organization of Bacterial Glutamine Synthetase
  • 00:00
    102. Page 850
  • 00:03
    103. Allosteric Regulation of Glutamine Synthetase by Feedback Inhibition
  • 00:03
    104. Covalent Modification of GS: Adenylylation of Tyr397 in the Glutamine Synthetase
  • 00:12
    105. The cyclic cascade system regulating the covalent modification of GS
  • 00:33
    106. The cyclic cascade system regulating the covalent modification of GS
  • 04:15
    107. Gene Expression Regulates GS
  • 00:00
    108. The cyclic cascade system regulating the covalent modification of GS
  • 00:00
    109. The cyclic cascade system regulating the covalent modification of GS
  • 00:00
    110. Covalent Modification of GS: Adenylylation of Tyr397 in the Glutamine Synthetase
  • 00:00
    111. Allosteric Regulation of Glutamine Synthetase by Feedback Inhibition
  • 01:20
    112. Page 850
  • 00:01
    113. Allosteric Regulation of Glutamine Synthetase by Feedback Inhibition
  • 00:00
    114. Covalent Modification of GS: Adenylylation of Tyr397 in the Glutamine Synthetase
  • 00:00
    115. The cyclic cascade system regulating the covalent modification of GS
  • 00:00
    116. The cyclic cascade system regulating the covalent modification of GS
  • 00:00
    117. Gene Expression Regulates GS
  • 01:30
    118. Glutamine in the Human Body
  • 04:08
    119. -Glutamine and Cancer: (New in 6th edition, 2017) Certain cancer cell lines are very sensitive to glutamine deprivation. Blocking the use of glutamine for anabolic purposes as potential anticancer drug.
  • 00:17
    120. Slide 24
  • 02:49
    121. How Do Organisms Synthesize Amino Acids?
  • 00:00
    122. Slide 26
  • 00:44
    123. Amino Acids Are Formed from a-Keto Acids by Transamination
  • 00:00
    124. Slide 26
  • 02:22
    125. How Do Organisms Synthesize Amino Acids?
  • 00:00
    126. Slide 26
  • 00:00
    127. Amino Acids Are Formed from a-Keto Acids by Transamination
  • 00:00
    128. Humans Can Synthesize Only 10 of the 20 Common Amino Acids
  • 00:01
    129. Page 855
  • 01:04
    130. Humans Can Synthesize Only 10 of the 20 Common Amino Acids
  • 00:00
    131. Amino Acids Are Formed from a-Keto Acids by Transamination
  • 00:00
    132. Slide 26
  • 02:33
    133. How Do Organisms Synthesize Amino Acids?
  • 01:26
    134. Slide 26
  • 00:08
    135. How Do Organisms Synthesize Amino Acids?
  • 00:11
    136. Slide 26
  • 05:14
    137. Amino Acids Are Formed from a-Keto Acids by Transamination
  • 00:05
    138. Humans Can Synthesize Only 10 of the 20 Common Amino Acids
  • 00:01
    139. Page 855
  • 00:03
    140. Humans Can Synthesize Only 10 of the 20 Common Amino Acids
  • 00:00
    141. Slide 1
  • 00:00
    142. Slide 3
  • 01:03
    143. The Nitrogen Cycle
  • 00:00
    144. How Do the Various Organic Forms of Nitrogen Arise?
  • 00:00
    145. Which Metabolic Pathways Allow Organisms to Live on Inorganic Forms of Nitrogen?
  • 00:00
    146. Nitrate Assimilation is the Principal Pathway for Ammonium Biosynthesis
  • 00:00
    147. Nitrogen Fixation Is by Nitrogenase Complex
  • 00:00
    148. The Fate of Ammonium
  • 00:00
    149. The Glutamate Dehydrogenase Reaction
  • 00:07
    150. The Fate of Ammonium
  • 00:55
    151. The Glutamate Dehydrogenase Reaction
  • 00:00
    152. The Fate of Ammonium
  • 00:00
    153. Nitrogen Fixation Is by Nitrogenase Complex
  • 00:00
    154. Nitrate Assimilation is the Principal Pathway for Ammonium Biosynthesis
  • 00:00
    155. Which Metabolic Pathways Allow Organisms to Live on Inorganic Forms of Nitrogen?
  • 00:00
    156. How Do the Various Organic Forms of Nitrogen Arise?
  • 00:12
    157. The Nitrogen Cycle
  • 00:01
    158. How Do the Various Organic Forms of Nitrogen Arise?
  • 00:02
    159. Which Metabolic Pathways Allow Organisms to Live on Inorganic Forms of Nitrogen?
  • 00:00
    160. Nitrate Assimilation is the Principal Pathway for Ammonium Biosynthesis
  • 00:00
    161. Nitrogen Fixation Is by Nitrogenase Complex
  • 00:00
    162. The Fate of Ammonium
  • 00:48
    163. The Glutamate Dehydrogenase Reaction
  • 01:19
    164. The enzymatic reaction catalyzed by glutamine synthetase
  • 00:01
    165. The Major Pathways of Ammonium Assimilation Lead to Glutamine Synthesis
  • 00:41
    166. The GDH/GS Pathway of Ammonium Assimilation
  • 01:54
    167. The GS/GOGAT Pathway of Ammonium Assimilation
  • 00:48
    168. The Subunit Organization of Bacterial Glutamine Synthetase
  • 00:31
    169. Page 850
  • 01:02
    170. Allosteric Regulation of Glutamine Synthetase by Feedback Inhibition
  • 00:40
    171. Covalent Modification of GS: Adenylylation of Tyr397 in the Glutamine Synthetase
  • 01:22
    172. The cyclic cascade system regulating the covalent modification of GS
  • 00:14
    173. The cyclic cascade system regulating the covalent modification of GS
  • 02:45
    174. Gene Expression Regulates GS
  • 01:26
    175. Glutamine in the Human Body
  • 00:55
    176. -Glutamine and Cancer: (New in 6th edition, 2017) Certain cancer cell lines are very sensitive to glutamine deprivation. Blocking the use of glutamine for anabolic purposes as potential anticancer drug.
  • 00:02
    177. Slide 24
  • 02:52
    178. How Do Organisms Synthesize Amino Acids?
  • 00:15
    179. Slide 26
  • 01:47
    180. Amino Acids Are Formed from a-Keto Acids by Transamination
  • 01:25
    181. Humans Can Synthesize Only 10 of the 20 Common Amino Acids
  • 03:36
    182. Page 855
  • 00:01
    183. The Pathways of Amino Acid Biosynthesis Can Be Organized into Families
  • 00:03
    184. Page 857
  • 00:01
    185. The Pathways of Amino Acid Biosynthesis Can Be Organized into Families
  • 01:58
    186. Page 855
  • 03:19
    187. The Pathways of Amino Acid Biosynthesis Can Be Organized into Families
  • 00:13
    188. Page 857
  • 01:58
    189. Slide 32
  • 00:32
    190. Page 857
  • 00:18
    191. Slide 32
  • 00:31
    192. Page 858
  • 00:36
    193. Page 862
  • 01:04
    194. Page 861
  • 02:03
    195. Page 863
  • 01:14
    196. Page 864
  • 04:30
    197. Asparagine and Leukemia
  • 01:06
    198. The Pathways of Amino Acid Biosynthesis Can Be Organized into Families
  • 00:27
    199. Page 857
  • 00:20
    200. Slide 32
  • 00:13
    201. Page 858
  • 00:09
    202. Page 862
  • 01:53
    203. Page 861
  • 00:18
    204. Page 863
  • 01:32
    205. Page 864
  • 02:49
    206. Asparagine and Leukemia
  • 00:09
    207. Biosynthesis of Thr, Met, and Lys Proceed From Aspartate
  • 00:00
    208. Asparagine and Leukemia
  • 00:00
    209. Page 864
  • 00:00
    210. Page 863
  • 00:29
    211. Page 861
  • 00:00
    212. Page 863
  • 00:00
    213. Page 864
  • 00:00
    214. Asparagine and Leukemia
  • 00:40
    215. Biosynthesis of Thr, Met, and Lys Proceed From Aspartate
  • 00:09
    216. Page 865
  • 00:09
    217. Page 865
  • 00:01
    218. Page 865
  • 00:01
    219. Biosynthesis of Thr, Met, and Lys Proceed From Aspartate
  • 00:08
    220. Page 865
  • 00:11
    221. Page 865
  • 02:41
    222. Page 866
  • 01:12
    223. Page 866
  • 01:12
    224. Page 867
  • 00:23
    225. Page 869 & 870
  • 00:31
    226. Page 869
  • 00:03
    227. Page 869 & 870
  • 00:07
    228. Page 869
  • 01:35
    229. Page 869 & 870
  • 01:56
    230. Page 870
  • 00:25
    231. Page 870
  • 00:00
    232. Page 870
  • 00:54
    233. Page 869 & 870
  • 00:03
    234. Page 870
  • 00:00
    235. Page 869 & 870
  • 00:00
    236. Page 869
  • 01:08
    237. Page 869 & 870
  • 00:01
    238. Page 869
  • 00:02
    239. Page 869 & 870
  • 00:01
    240. Page 870
  • 00:03
    241. Page 870
  • 00:23
    242. Cysteine Biosynthesis is Accomplished Via Sulfhydryl Transfer to Serine
  • 00:25
    243. 5
  • 00:30
    244. Page 873
  • 00:21
    245. Page 872
  • 00:47
    246. Slide 54
  • 00:00
    247. Page 872
  • 00:00
    248. Page 873
  • 00:17
    249. 5
  • 00:00
    250. Page 873
  • 00:00
    251. Page 872
  • 00:00
    252. Slide 54
  • 08:23
    253. Slide 55
  • 07:33
    254. Amino Acid Biosynthesis Inhibitors as Herbicides
  • 00:01
    255. The Urea Cycle
  • 00:02
    256. Amino Acid Biosynthesis Inhibitors as Herbicides
  • 07:19
    257. The Urea Cycle
  • 00:06
    258. Alanine Transports Ammonia from Muscles to the Liver
  • 00:22
    259. The Urea Cycle
  • 00:50
    260. Alanine Transports Ammonia from Muscles to the Liver
  • 00:01
    261. The Urea Cycle
  • 00:00
    262. Alanine Transports Ammonia from Muscles to the Liver
  • 02:07
    263. Slide 59
  • 01:48
    264. The TCA Cycle and Urea Cycle Can Be linked
  • 01:24
    265. Slide 61
  • 00:02
    266. Page 883
  • 00:14
    267. Page 884
  • 00:09
    268. Page 883
  • 02:01
    269. Page 884
  • 00:28
    270. *Maple syrup urine disease (楓漿尿病) (page 883)*Alkaptonuria (黑尿症)(page 885)*Phenylketonuria (苯丙酮尿症)(page 885)
  • 00:00
    271. Page 884
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    272. Page 883
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    273. Page 883
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    274. Page 883
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    275. Page 884
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    276. Page 883
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    277. Page 883
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    278. Page 883
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    279. Page 884
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    280. *Maple syrup urine disease (楓漿尿病) (page 883)*Alkaptonuria (黑尿症)(page 885)*Phenylketonuria (苯丙酮尿症)(page 885)
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    281. Page 885
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    282. *Phenylketonuria (PKU)(苯丙酮尿症)
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    283. Slide 76
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